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Altace (generic name: ramipril; brand names include: Cardace / Tritace / Ramace / Lopace) is a type of medicine called an ACE inhibitor. ACE inhibitors help to reduce blood pressure by decreasing production of a protein in the human body that can cause the blood vessels to constrict.
Altace is indicated for the treatment of:
High blood pressure (hypertension)
Congestive heart failure
Altace is also used to improve survival in patients with heart failure after a heart attack (myocardial infarction).
Altace is the only ACE inhibitor proven to reduce the risk of having a heart attack or stroke in people aged 55 or older who have any combination of the following serious cardiovascular (heart-related) risk factors:
Diabetes plus one other risk factor (high blood pressure, high cholesterol, or a habit of cigarette smoking)
Coronary artery disease
Previous heart attack
Peripheral vascular disease
In the Heart Outcomes Prevention Evaluation (HOPE) study, Altace reduced the risk of cardiovascular disease for people aged 55 and older who had normal blood pressure or whose high blood pressure was already being treated. Altace reduced the relative risk of heart attack by 20%; death from cardiovascular problems by 26%; and stroke by 32%.